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    • Cox-2 Woes Fuel Drug Ad Debate Direct-to-consumer advertising of the cox-2 prescription painkillers Vioxx and Celebrex helped catapault worldwide sales of the drugs into the billions. Vioxx Fans Have Their Say Patients who rely on painkillers like Bextra and Celebrex are seeking more relief. Cox-2 Woes Fuel Drug Ad Debate Direct-to-consumer advertising of the cox-2 prescription painkillers Vioxx and Celebrex helped catapault worldwide sales of the drugs into the billions. Vioxx Fans Have Their Say Patients who rely on painkillers like Bextra and Celebrex are seeking more relief.

      Cox-2 Woes Fuel Drug Ad Debate Direct-to-consumer advertising of the cox-2 prescription painkillers Vioxx and Celebrex helped catapault worldwide sales of the drugs into the billions. Patients in the cancer study were taking 400 milligrams to 800 milligrams of Celebrex daily or placebos, Pfizer said in a news release. With the FDA Public Health Advisory statement that clinical trials showed drugs such as Vioxx and Celebrex might be associated with an increased risk of serious health problems, people have been wondering where to turn for safe and effective pain relief.